Comparative therapeutic evaluation of 308 nm monochromatic excimer light in combination with calcipotriol ointment vs 308 nm monochromatic excimer light alone in palmoplantar psoriasis

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Treatment of palmoplantar psoriasis with monochromatic excimer light (308-nm) versus cream PUVA.

Palmoplantar psoriasis is a chronic disease, which is very resistant to treatment and often leads to severe disabilities. Photochemotherapy employing psoralens combined with UVA irradiation (PUVA) is a well-accepted therapy for palmoplantar psoriasis. Its topical application (bath PUVA; cream PUVA) avoids the typical side effects of orally applied psoralens. We compared the efficacy of cream PU...

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Monochromatic excimer light 308 nm in the treatment of vitiligo: a pilot study.

OBJECTIVE To study the efficacy and safety of monochromatic excimer light (MEL) on 37 vitiligo patients referred to our clinic. METHODS In a pilot study, 37 patients (17 males, 20 females) with acrofacial (n=21), focal (n=11), segmental (n=1), and generalized (n=4) vitiligo were treated twice weekly with MEL for a maximum period of 6 months. RESULTS Thirty-five patients (95%) showed signs o...

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Improvement of Anti-TNF-α Antibody-Induced Palmoplantar Pustular Psoriasis Using a 308-nm Excimer Light

Anti-tumor necrosis factor (TNF)-α antibody is utilized in the treatment of a variety of chronic inflammatory conditions, including psoriasis. However, it can induce paradoxical development and/or exacerbation of psoriasis in the course of anti-TNF-α antibody treatment, which is sometimes refractory to conventional treatments. Herein, we report a case of refractory palmoplantar pustular psorias...

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Monochromatic Excimer Light for the Treatment of Palmoplantar Psoriasis

Palmoplantar psoriasis (PPP) presents with typical scaly patches sometimes studded with sterile pustules. It is chronic and recalcitrant to therapy; it often causes itching, burning, painful ragades and can lead to severe disabilities (1). Some preliminary works (2-4) have established that an excimer laser-generated 308 nm UVB radiation is effective in the treatment of psoriasis. In our study, ...

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Treatment of inverse psoriasis with the 308 nm excimer laser.

BACKGROUND The treatment of inverse psoriasis can be both challenging and frustrating. Conventional topical and systemic treatments can be limited in terms of efficacy, acceptability and safety. The 308 nm excimer laser has been shown to be effective in the treatment of psoriatic plaques. METHODS A patient with chronic inverse psoriasis was treated with 308 nm excimer laser using a 3.5 cm spo...

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ژورنال

عنوان ژورنال: International Journal of Research in Dermatology

سال: 2019

ISSN: 2455-4529

DOI: 10.18203/issn.2455-4529.intjresdermatol20190038